Hirota, K., Kitade, Y., Senda, S., Halat, M. J., Watanabe, K. A. and Fox, J. J., A Novel Pyrimidine to Pyridine Ring Transformation Reaction. A Facile Synthesis of 2,6-Dihydroxypyridines, J. Am. Chem. Soc., 101, 4423-4425 (1979). 【IF: 10.677】
Hirota, K., Kitade, Y. and Senda, S., A Novel Synthesis of Pyrido[2,3-d]pyrimidines by Reaction of Uracils with 6-Aminouracils via Pyrimidine-to-pyridine Transformation, Heterocycles, 14, 407-410 (1980).【IF:0.908】
Hirota, H., Kitade, Y. and Senda, S., A Novel Ring Transformation of Uracil into the Benzene Ring System, J. Heterocycl. Chem., 17, 413-414 (1980).【IF: 1.224】
Hirota, K., Kitade, Y. and Senda, S., A Novel Ring Transformation of 5-Nitrouracils into 5-Carbamoyluracils via the Retro-Michael Reaction, Tetrahedron Lett., 22, 2409-2410 (1981). 【IF: 2.391】
Hirota, H., Yamada, Y., Kitade, Y. and Senda, S., Pyrimidine Derivatives and Related Compounds. Part 37. Novel Nucleophilic Substitutions of 5-Bromo-6-methyluracils or 5-Bromo-6-bromomethyluracils with Aromatic Amines, J. Chem. Soc., Perkin Trans. 1, 2943-2947 (1981).【IF: 2.181】
Hirota, K., Kitade, Y., Senda, S., Halat, M. J., Watanabe, K. A. and Fox, J. J., Pyrimidines. 17. Novel Pyrimidine to Pyridine Transformation Reaction. One-Step Synthesis of Pyrido[2,3-d]pyrimidines, J. Org. Chem., 46, 846-851 (1981).【IF: 4.638】
Hirota, K., Kitade, Y. and Senda, S., Pyrimidine Derivatives and Related Compounds. 39. A Novel Cycloaromatization Reaction of 5-Formyl-1,3-dimethyluracil with Three-Carbon Nucleophiles. Synthesis of Substituted 4-Hydroxybenzoates, J. Org. Chem., 46, 3949-3953 (1981).【IF: 4.638】
Hirota, K., Yamada, Y., Asao, T., Kitade, Y. and Senda, S., Pyrimidine Derivatives and Related Compounds. XL. Synthesis of 7-Substituted Pyrimido[5,4-d]pyrimidines, Chem. Pharm. Bull., 29, 3060-3063 (1981).【IF: 1.564】
Hirota, K., Kitade, Y., Shimada, K. and Senda, S., A Ring Transformation of Uracil into the Pyrazole Ring System. Reinvestigation of the Reaction of 5-Formyluracils with Hydrazines, Chem. Pharm. Bull., 29, 3760-3762 (1981).【IF: 1.564】
Hirota, K., Sugiyama, T., Kitade, Y., Senda, S. and Maki, Y., A Facile Synthesis of 7-Hydroxy-9-deazaxanthines, Synthesis, 1097-1100 (1982).【IF: 0.649】
Hirota, K., Kitade, Y., Iwami, F., Senda, S. and Maki, Y., A Direct Synthesis of 2',5'-Dihalo-2',5'-dideoxyuridines from Uridine Derivatives, Synthesis, 121-122 (1983). 【IF: 0.649】
Hirota, K., Kitade, Y., Shimada, K., Senda, S. and Maki, Y., Pyrimidine Derivatives and Related Compounds. Part 45. Synthesis of 4-Allophanoylpyrazoles via a Pyrimidine-to-pyrazole Ring Transformation, J. Chem. Soc., Perkin Trans. 1, 1293-1297 (1983).【IF: 2.181】
Hirota, K., Kitade, Y., Tomishi, T. and Maki, Y., Simple Method for the Synthesis of 5-Substituted 2',5-Anhydro-2',5'-dideoxy-1-b-D-arabinofuranosyluracils, J. Chem. Soc., Chem. Commun., 108-109 (1984). 【IF: 6.718】
Hirota, K., Sugiyama, T., Kitade, Y., Senda, S. and Maki, Y., Pyrimidine Derivatives and Related Compounds. Part 47. A New Synthesis of Xanthines and Pyrrolo[3,2-d]pyrimidines by Intramolecular Cyclisation of 6-Substituted 5-Nitrouracil Derivatives, J. Chem. Soc., Perkin Trans. 1, 583-588 (1984).【IF: 2.181】
Hirota, K., Kitade, Y., and Senda, S., Pyrimidine Derivatives and Related Compounds. Part 48. Uracil Ring Transformation: Conversion of 5-Nitrouracils into 5-Carbamoyluracils, J. Chem. Soc., Perkin Trans. 1, 1859-1861 (1984). 【IF: 2.181】
Hirota, K., Kitade, Y., Iwami, F. and Senda, S., Pyrimidine Derivatives and Related Compounds. XLIX. Reaction of Anhydrouridines with the Vilsmeier Reagent, Chem. Pharm. Bull., 32, 2591-2595 (1984).【IF: 1.564】
Hirota, K., Kitade, Y., Sajiki, H. and Maki, Y., Novel Synthesis of 2-Thiocytosine Derivatives via Pyrimidine-to-pyrimidine Ring Transformation, Heterocycles, 22, 2259-2262 (1984). 【IF: 0.908】
Hirota, K., Kitade, Y., Sajiki, H. and Maki, Y., A Facile Synthesis of 7-Substituted Pyrimido[4,5-d]pyrimidine-2,4-diones, Synthesis, 589-590 (1984).【IF: 0.649】
Hirota, K., Kubo, K., Kitade, Y. and Maki, Y., Synthesis of Phidolopin, 7-(4-Hydroxy-3-nitrobenzyl)-1,3-dimethylxanthine from the Bryozoan Phidolopora Pacifica, Tetrahedron Lett., 26, 2355-2356 (1985). 【IF: 2.391】
Hirota, K., Kitade, Y. and Senda, S., Pyrimidines. LII. Synthesis of Pyrido[2,3-d]- pyrimidine-2,4-diones and Pyrido[2,3-d:6,5-d']dipyrimidine-2,4,6,8-tetrones, J. Heterocycl. Chem., 22, 345-347 (1985).【IF: 1.224】
Hirota, K., Kitade, Y., Shimada, K. and Maki, Y., Pyrimidines. 54. Ring Transformation of 5-(2-Carbamoylvinyl)uracil Derivatives to 5-Carbamoylpyridin-2-ones, J. Org. Chem., 50, 1512-1516 (1985).【IF: 4.638】
Hirota, K., Kitade, Y., Tomishi, T. and Maki, Y., Nucleosides. II. Direct Synthesis of 5-Substituted 2',5'-Anhydro-1-b-D-arabinofuranosyluracils from Uridine Derivatives, Chem. Pharm. Bull., 33, 4212-4215 (1985).【IF: 1.564】
Hirota, K., Kitade, Y., Tomishi, T. and Maki, Y., Nucleosides. Part 3. Synthesis of 2-N-Substituted 1-b-D-Arabinofuranosylisocytosine Derivatives by the reaction of 2',5'-Dichloro-2',5'-dideoxy-uridine with Amines, Nucleosides & Nucleotides, 4, 681-694 (1985).【IF: 0.713】
Hirota, K., Kitade, Y., Sajiki, H. and Maki, Y., Novel Reaction of 5-Nitro(or Carbamoyl)uracil Derivatives with Amines. Thermal Exchange Reaction of N1-Portion of the Uracils for Amines via Ring-opening and Ring-closure Processes, Tetrahedron Lett., 27, 3263-3266 (1986). 【IF: 2.391】
Alster, D., Brozda, D., Kitade, Y., Wong, A., Charubala, R., Pfleiderer, W. and Torrence, P. F., 2',5'-Phosphodiesterase Activity Depends Upon the Presence of a 3'-Hydroxy Moiety in the Penultimate Position of the Oligonucleotide Substrate, Biochem. Biophy. Res. Comm., 141, 555-561 (1986). 【IF: 2.281】
Hirota, K., Kitade, Y., Isobe, Y. and Maki, Y., Palladium Catalyzed Coupling of 5-Hydroxyuracil Trifluoromethanesulfonates (Triflates) with Alkenes and Alkynes, Heterocycles, 26, 355-358 (1987). 【IF:0.908】
Hirota, K., Isobe, Y., Kitade, Y. and Maki, Y., A Simple Synthesis of 5-(1-Alkenyl)uracil Derivatives by Palladium-Catalyzed Oxidative Coupling of Uracils with Olefins, Synthesis, 495-496 (1987).【IF: 0.649】
Hirota, K., Kitade, Y., Tomishi, T. and Maki, Y., New Chemical Modification of the Ribosyl Moiety in Uridines, Synthesis of Novel Types of 3',5'-Epithio Uridine Derivatives, J. Chem. Soc., Chem. Commun., 1801-1802 (1987). 【IF: 6.718】
Hirota, K., Kitade, Y., Tomishi, T., Maki, Y. and De Clercq, E., Nucleosides. Part 6. New Chemical Modification of the Ribosyl Moiety in Uridines; Synthesis of 2,2'-Anhydro- 1-[5-deoxy-5-(substituted thio)-b-D-arabinofuranosyl]uracil Derivatives and Their Conversion into 3',5'-Epithiopyrimidine Nucleosides, J. Chem. Soc., Perkin Trans. 1, 2233-2241 (1988).【IF: 2.181】
Maki, Y., Shimada, K., Sako, M., Kitade, Y. and Hirota, K., Photochemical Oxidation of 4-Ethoxy-2-methyl-5-morpholino-3(2H)-pyridazinone (Emorfazone) by Pyrimido- [5,4-g]pteridine 5-Oxides. An Attempt to Apply a Functional Chemical Model for Biological Oxidations to Drug-Metabolism Studies, Chem. Pharm. Bull., 36, 1714-1720 (1988).【IF: 1.564】
Hirota, K., Abe, Y., Asao, T., Senda, S., Kitade, Y. and Maki, Y., Ring Transformation of Pyrimidines to Pyridines. Synthesis of 4-Alkylaminopyridin-2-ones by Alkaline Hydrolysis of 6-(2-Dimethyl-aminovinyl)uracils, J. Heterocycl. Chem., 25, 985-990 (1988).【IF: 1.224】
Hirota, K., Sajiki, H., Kitade, Y. and Maki, Y., Rearrangement of 5-Cyanouracils into 6-Aminouracils by Reaction with Amines and Hydroxide Ion, Chem. Pharm. Bull., 37, 2008-2011 (1989).【IF: 1.564】
Hirota, K., Sajiki, H., Kitade, Y. and Maki, Y., A Novel Ring Transformation of 5-Carbamoyluracils into Barbituric Acids, J. Chem. Soc., Perkin Trans. 1, 1695-1697 (1989). 【IF: 2.181】
Maki, Y., Sako, M., Oyabu, I., Murase, T., Kitade, Y. and Hirota, K., Photo-oxidative Decarboxylation of Phenylacetic Acids induced by Pyrimido[5,4-g]pteridine-10-oxide involving a Single-electron-transfer Process in Both Stages, J. Chem. Soc., Chem. Commun., 1780-1782 (1989). 【IF: 6.718】
Maki, Y., Oyabu, I., Ohara, S., Sako, M., Kitade, Y. and Hirota, K., Photooxidative Decarboxylation of Indole-3-acetic Acid by Pyrimido[5,4-g]pteridine N-Oxide as a Biomimetic Reaction, Chem. Pharm. Bull., 37, 3239-3242 (1989).【IF: 1.564】
Hirota, K., Sajiki, H., Kitade, Y. and Maki, Y., Novel Ring Transformations of 5-Cyanouracils into 2-Thiocytosines, 2,4-Diaminopyrimidines, and Pyrimido[4,5-d]pyrimidines by the Reaction with Thioureas and Guanidines, J. Chem. Soc., Perkin Trans. 1, 123-128 (1990).【IF: 2.181】
Maki, Y., Sako, M., Murase, T., Kitade, Y. and Hirota, K., Photochemical Oxygenation of Olefins by Heterocyclic N-Oxides: Mechanistic Characteristics in the Photochemistry of Pyrimido[5,4-g]-pteridine-10-oxide, Heterocycles, 30, 279-282 (1990). 【IF:0.908】
Hirota, K., Kitade, Y., Sajiki, H. and Maki, Y., Novel Reaction of Uracil Derivatives Possessing Electron-withdrawing Groups at the 5-Position with Amines: Exchange Reaction between the N1-Portion of Uracils and Amines, J. Chem. Soc., Perkin Trans. 1, 367-373 (1990).【IF: 2.181】
Hirota, K., Sajiki, H., Ni, P.-Z., Kitade, Y. and Maki, Y., Novel Intramolecular Rearrangement of 5-Carbamoyluracils into Barbituric Acids, Tetrahedron, 46, 3431-3438 (1990). 【IF: 2.803】
Hirota, K., Hosono, H., Kitade, Y., Maki, Y., Chu, C. K., Schinazi, R. F., Nakane, F. and Ono, K., Synthesis and Anti-human Immunodeficiency Virus (HIV-1) Activity of 3'-Deoxy-3'-(triazol-1-yl)-thymidines and 2',3'-Dideoxy-3'-(triazol-1-yl)uridines, and Inhibition of Reverse Transcriptase by Their 5’-Triphosphates, Chem. Pharm. Bull., 38, 2597-2601 (1990).【IF: 1.564】
Kitade, Y., Nakanishi, R., Sako, M., Hirota, K. and Maki, Y., Facile Conversion of N6-Benzoyl-adenosine into 5'-Chloro-5'-deoxy-8-hydroxyadenosines by a Reaction with Cupric Chloride: A Prominent Substituent Effect of the N6-Benzoyl Group, Chem. Pharm. Bull., 39, 1902-1904 (1991).【IF: 1.564】
Kitade, Y., Nakata, Y., Hirota, K., Maki, Y., Pabuccuoglu, A. and Torrence, P. F., 8-Methyladenosine-substituted Analogues of 2-5A: Synthesis and their Biological Activities, Nucleic Acids Res., 19, 4103-4108 (1991).【IF: 8.278】
Kitade, Y., Alster, D. K., Pabuccuoglu, A. and Torrence, P. F., Uridine Anaolgs of 2',5'-Oligoadenylates: On the Biological Role of the Middle Base of 2-5A Trimer, Bioorganic Chem., 19, 283-299 (1991).【IF: 1.732】
Kitade, Y., Suzuki, A., Hirota, K., Maki, Y., Nakane, H., Ono, K., Baba, M. and Shigeta, S., Synthesis and Anti-human Immunodeficiency Virus Type 1 (HIV-1) Activity of 3-Substituted Derivatives of 3'-Azido-3'-deoxythymidine (AZT), and Inhibition of HIV-1 Reverse Transcriptase by Their 5'-Triphosphates, Chem. Pharm. Bull., 40, 920-924 (1992). 【IF: 1.564】
Kitade, Y., Makino, T., Hirota, K. and Maki, Y., Oxidative Cyclization of 2',3'-O-Isopropylideneadenosines into 5'-O,8-Cycloadenosines with Lead Tetraacetate: Remarkable Effect of N6-Substituents on the Oxidation, Nucleosides & Nucleotides, 11, 365-372 (1992).【IF: 0.713】
Hirota, K., Kitade, Y., Kanbe, Y. and Maki, Y., Convenient Method for the Synthesis of C-Alkylated Purine Nucleosides: Palladium-Catalyzed Cross-Coupling Reaction of Halogenopurine Nucleosides with Trialkylaluminums, J. Org. Chem., 57, 5268-5270 (1992).【IF: 4.638】
Hirota, K., Ni, P.-Z., Suzuki, A., Takasu, H., Kitade, Y. and Maki, Y., The Dimroth Rearrangement of 6-Aminouracil Derivatives, Chem. Pharm. Bull., 40, 2839-2841 (1992).【IF: 1.564】
Hirota, K., Hosono, H., Kitade, Y., Maki, Y., Chu, C. K., Schinazi, R. F. and Muraoka, O., Synthesis of Thymidine Derivatives 3'-Modified with a Polar Three-Atoms Groups as Potential Anti-HIV-1 Agents, Nucleosides & Nucleotides, 11, 1731-1738 (1992).【IF: 0.713】
Sako, M., Makino, T., Kitade, Y., Hirota, K. and Maki, Y., N6-Substituent Effect on the Photooxidation of 2',3'-O-Isopropylideneadenosines with a Pyrimido[5,4-g]-pteridinetetraone N-Oxide. Chemical Evidence for the Generation and Reactivity of Adenosyl Cation Radicals, J. Chem. Soc., Perkin Trans. 1, 1801-1805 (1992).【IF: 2.181】
Hirota, K., Kitade, Y., Kanbe, Y., Isobe, Y. and Maki, Y., Facile Synthesis of Thymidine Derivatives by Cross-coupling of 5-Halogenouridine Derivatives with Trimethylaluminum, Synthesis, 213-215 (1993). 【IF: 0.649】
Kitade, Y., Hirota, K. and Maki, Y., Diversity of Intramolecular Rearrangements of Uracil Derivatives to Pyrazolones and Hydantoins governed by a Prominent 5-Substituent Effect, J. Chem. Res. (S), 2-3; J. Chem. Res. (M), 0101-0112 (1993).【IF: 0.596】
Kitade, Y., Hirota, K. and Maki, Y., Reductive Cleavage of the Ribose Moiety in Purine Nucleosides using Diisobutylaluminum Hydride: A New Method for the Preparation of Acyclonucleosides, Tetrahedron Lett., 34, 4835-4836 (1993).【IF: 2.391】
Kitade, Y., Monguchi, Y., Hirota, K. and Maki, Y., Synthesis of a Ring-Scission Analogue of Neplanocin A as a Potential Inhibitor of S-Adenosylhomocysteine Hydrolase, Tetrahedron Lett., 34, 6579-6580 (1993).【IF: 2.391】
Kitade, Y., Takeda, Y., Hirota, K. and Maki, Y., Photoinduced Electron-Transfer Oxygenation of 7-Methyl-9-(b-D-ribofuranosyl)guaninium Salts: A Prominent Effect of Iodide Anion, Tetrahedron Lett., 36, 2633-2636 (1995). 【IF: 2.391】
Yang, J.-P., Merin, J. P., Nakano, T., Kato, T., Kitade, Y. and Okamoto, T., Inhibition of the DNA-binding Activity of NF-kB by Gold Compounds in vitro, FEBS Lett., 361, 89-96 (1995).【IF: 3.582】
Ito, K. Kitade, Y. and Yatome, C., A Pathway for Biodegradation of an Anthraquinone Dye, C. I. Disperse Red 15, by a Yeast Strain Pichia anomala, Bull. Environ. Contam. Toxicol., 56, 413-418 (1996).【IF: 1.105】
Hirota, K., Kubo, K., Sajiki, H., Kitade, Y., Sako, M. and Maki, Y., Reactivity of Thioaldehyde: Cyclization Reaction of 6-Amino-1,3-demethyl-5-thioformyluracil with Enamines into Pyrido[2,3-d]pyrimidine-2,4-(1H,3H)-diones, J. Org. Chem., 62, 2999-3001 (1997).【IF: 4.638】
Kitade, Y., Hayashi, M., Yatome, C., Chajima, M. and Nagase, H., Inhibitiory Effect on HT-1080 Tumor cell Invasion in vitro Using 9-(2’-Hydroxyethyl)adenine 2’-Phosphates, Bioorg. Med. Chem. Lett., 7, 833-836 (1997). 【IF: 2.331】
Hirota, K., Monguchi, Y., Sajiki, H. and Kitade, Y., A Novel Approach for the Synthesis of Purine Acyclonucleosides Using 9-D-Ribitylpurines as a Chiral Pool, Synlett, 697-698 (1997).【IF: 2.655】
Hirota, H., Monguchi, Y., Kitade, Y. and Sajiki, H., Ribofuranose-ring Cleavage of Purine Nucleosides with Diisobutylaluminum Hydride: A Convenient Method for the Preparation of Purine Acyclonucleosides, Tetrahedron, 53, 16683-16698 (1997). 【IF: 2.803】
Hirota, H., Nakazawa, Y., Kitade, Y. and Sajiki, H., Convenient Synthesis of Pyrido[4,3-d]pyrimidine-2,4(1H,3H)-diones, Heterocycles, 47, 871-882 (1998). 【IF:0.908】
Tanaka, H., Tanaka, T., Hosoya, A., Kitade, Y. and Etoh, H., An Isoflavan from Erythrina X Bidwillii, Phytochemistry, 47, 1397-1400 (1998).【IF: 3.050】
Kitade, Y., Saito, N., Kozaki, A., Takahashi, K., Yatome, C., Takeda, Y., Sajiki, H. and Hirota, K., Facile Method for the Preparation of 7-Methyl-8-oxoguanosines as an Immunomodulator, Nucleosides & Nucleotides, 17, 91-97 (1998).【IF: 0.713】
Tanaka, H., Tanaka, T., Hosoya, A., Kitade, Y. and Etoh, H., Three Isoflavones from Erytherina Orientalis, Phytochemistry, 48, 355-357 (1998).【IF: 3.050】
Hirota, K., Monguchi, Y., Sajiki, H., Sako, M. and Kitade, Y., Novel Synthesis of Purine Acyclonucleosides Possessing a Chiral 9-Hydroxyalkyl Group by Sugar Modification of 9-D-Ribitylpurines, J. Chem. Soc., Perkin Trans 1, 941-946 (1998). 【IF: 2.181】
Hirota, K., Monguchi, Y., Sajiki, H., Yatome, C., Hiraoka, A. and Kitade, Y., A Convenient Synthesis of Acyclic Adenosines with an Unsaturated Side Chain by Modification of 9-(2,3-O-Isopropylidene-D-ribityl)adenine, Nucleosides & Nucleotides., 17, 1333-1345 (1998).【IF: 0.713】
Itoh, K., Kitade, Y., Kobanashi, S., Nakanishi, M. and Yatome, C., Demethylation of Acridine Orange by Arthrobacter globiformis, Bull. Environ. Contam. Toxicol., 60, 781-785 (1998). 【IF: 1.105】
Itoh, K., Kitade, Y. and Yatome, C., Oxidative Biodegradation of an Anthraquinone dye, Pigment Violet 12, by Coriolus vesicolor, Bull. Environ. Contam. Toxicol., 60, 786-790 (1998).【IF: 1.105】
Kitade, Y., Wakana, M., Terai, S., Tsuboi, T., Nakanishi, M., Yatome, C., Dong, B., Silverman, R. H. and Torrence, P. F., 2-Bromoadenosine-substituted 2´,5´-Oligoadenylates Modulate Binding and Activation Abilities of Human Recombinant RNase L, Nucleosides & Nucleotides, 17, 2323-2333 (1998). 【IF: 0.713】
Hirota, K., Kubo, K., Kitade, Y. and Sajiki, H., Reduction of Uracil Derivatives with an NADH Model, 1-Benzoyl-1,4-dihydronicotinamide, Heterocycles, 49, 475-479 (1998). 【IF:0.908】
Kitade, Y., Nakanishi, M. and Yatome, C., 9-[(2’S,3’S)-3’-Formyl-2’,3’-dihydroxypropyl]- adenine: A Facile Affinity-Labeling Probe of Human S-Adenosyl-L-homocysteine Hydrolase, Bioorg. Med. Chem. Lett., 9, 2737-2740 (1999). 【IF: 2.331】
Kitade, Y., Wakana, M., Tsuboi, T., Yatome, C., Bayly, S. F., Player, M. R. and Torrence, P. F., 2-Methyladenosine-substituted 2´,5´-Oligoadenylates: Conformations, 2-5A Binding and Catalytic Activities with Human Ribonuclease L, Bioorg. Med. Chem. Lett.,10, 329-331(2000). 【IF: 2.331】
Nakanishi, M., Iwata, A., Yatome, C. and Kitade, Y., Purification and Properties of Recombinant Plasmodium falciparum S-Adenosyl-L-homocysteine Hydrolase, J. Biochem., 29, 101-105 (2001). 【IF:3.073】
Kitade, Y., Kozaki, A. and Yatome, C., Facile Synthesis of 9-[(1’R,2’S)-2’-Hydroxy- 3’-oxocyclopentan-1’-yl]-9-H- adenine possessing Inhibitory Activity against Human Recombinant S-Adenosyl-L-homocysteine Hydrolase, Tetrahedron Lett., 42, 433-435 (2001). 【IF: 2.391】
Nakanishi, M., Yatome, C. , Ishida N. and Kitade, Y., Putative ACP Phosphodiesterase Gene (acpD) encodes an Azoreductase, J. Biol. Chem., 276, 46394-46399 (2001). 【IF: 4.600】
Kitade, Y., Kozaki, A., Miwa, T. and Nakanishi, M., Synthesis of Base-modified Noraristeromycin Derivatives and their Inhibitory Activity against Human and Plasmodium falciparum Recombinant S-Adenosyl-L-homocysteine Hydrolase, Tetrahedron, 58, 1271-1277 (2002). 【IF: 2.803】
Itoh, K., Kitade, Y., Nakanishi, M. and Yatome, C., Decolorization of Methyl Red by a Mixed Culture of Bacillus sp. and Pseudomonas stutzeri, J. Environ. Sci. Health Part A Tox. Hazard Subst. Environ. Eng., 37, 415-421 (2002). 【IF: 1.135】
Yoshimura, A., Nakanishi, M., Yatome, C. and Kitade, Y., Comparative Study on Biological Properties of 2’,5’-Oligoadenylate Derivatives with Purified Human RNase L Expressed in E. coli, J. Biochem., 132, 643-648 (2002). 【IF:3.073】
Ueno, Y., Shibata, A., Matsuda, A. and Kitade, Y., Synthesis of 3’-3’-linked oligonucleotides branched by a pentaerythritol linker and the thermal stabilities of the triplexes with single-stranded DNA or RNA, Bioconjugate Chem., 14, 684-689 (2003). 【IF: 4.580】
Ueno, Y., Kato, Y., Okatani, S., Ishida, N., Nakanishi, M. and Kitade, Y., Synthesis of antisense oligonucleotides carrying modified 2-5A molecules at their 5’-termini and their properties, Bioconjugate Chem., 14, 690-696 (2003). 【IF: 4.580】
Ueno, Y., Okatani, S., Yamada, Y., and Kitade, Y., Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L, Bioorg. Med. Chem. Lett., 13, 3959-3961 (2003). 【IF: 2.331】
Kitade, Y., Kojima, H., Zulfiqar, F., Kim, H.-S., and Wataya, Y., Synthesis of 2-Fluoronoraristeromycin and its Inhibitory Activity against Plasmodium falciparum S-Adenosyl-L-homocysteine Hydrolase, Bioorg. Med. Chem. Lett., 13, 3963-3965 (2003). 【IF: 2.331】
Ueno, Y., Yamada, Y., Nakanishi, M., and Kitade, Y., A Specific Substrate-inhibitor, a 2'-Deoxy-2'-fluorouridine-containing Oligoribonucleotide, against Human RNase L, Bioorg. Med. Chem., 11, 5069-5073 (2003). 【IF: 2.951】
Tanaka, N., Kusakabe, Y., Shiraiwa, K., Sakamoto, Y., Nakanishi, M., Kitade, Y., and Nakamura, T., Crystallization and Preliminary X-ray Crystallographic Analysis of Plasmodium falciparum S-Adenosyl-L-homocysteine Hydrolase, Protein & Peptide Lett., 11, 201-205 (2004). 【IF: 1.735】
Hatanaka, K., Suzuki, K., Miura, Y., Yoshida, K., Ohnami, S., Kitade, Y., Yoshida, T., and Aoki, K., Interferon-alpha and Antisense K-ras RNA Combination Gene Therapy against Pancreatic Cancer, J. Gene Medicine, 6, 1139-1148 (2004). 【IF:1.953】
Nakanishi, M., Yoshimura, A., Ishida, N., Ueno, Y., and Kitade, Y., Contribution of Tyr712 and Phe716 to the Activity of Human RNase L, Eur. J. Biochem., 271, 2737-2744 (2004) . 【IF: 3.986】
Ueno, Y., Ishihara, S., Ito, Y., and Kitade, Y., Synthesis of 2’,5’-Oligoadenylate Analogs Containing an Adenine Acyclonucleoside and their Ability to activate Human RNase L, Bioorg. Med. Chem. Lett., 14, 4431-4434 (2004). 【IF: 2.331】
Tanaka, N., Nakanishi, M., Kusakabe, Y., Shiraiwa, K., Yabe, S., Ito, Y., Kitade,Y. and Nakamura, K., Crystal Structure of S-Adenosyl-L-homocysteine Hydrolase from the Human Malaria Parasite Plasmodium falciparum, J. Mol. Biol. 343, 1007-1017 (2004). 【IF: 3.959】
Tanaka, N., Nakanishi, M., Kusakabe, Y., Goto, Y., Kitade,Y. and Nakamura, K., Structural Basis for Recognition of 2’,5’-Linked Oligoadenylates by Human Ribonuclease L, EMBO J., 23, 3929-3938 (2004). 【IF:10.748】
Ueno, Y., Shibata, A., Matsuda, A., and Kitade, Y., Thermal Stability of Triple Helical DNAs containing 2’-Deoxyinosine and 2’-Deoxyxanthosine, Bioorg. Med. Chem., 12, 6581-6586 (2004). 【IF: 2.951】
Ito, K., Nakanishi, M., Lee, W.-C., Sasaki, H., Zenno, S., Saigo, K., Kitade, Y., Tanokura, M., Crystallization and preliminary X-ray analysis of AzoR (Azo Reductase) from Escherichia coli, Acta Crystallogr. F., F61, 399-402 (2005). 【IF: 0.568】
Takagi, C., Sukeda, M., Kim, H.-S., Wataya, Y., Yabe, S., Kitade, Y., Matsuda, M., Shuto, S., Synthesis of 5’-Methylenearisteromycin and its 2-Fluoro Derivative with Potent Antimalarial Activity due to Inhibition of the Parasite S-Adenosylhomocysteine Hydrolase, Org. Biomol. Chem., 3, 1245-1251 (2005). 【IF: 3.487】
Ueno, Y., Naito, T., Kawada, K., Shibata, A., Kim1, H.-S., Wataya, Y., and Kitade, Y., Synthesis of novel siRNAs having thymidine dimers consisting of a carbamate or an urea linkage at their 3’ overhang regions and their ability to suppress human RNase L protein expression, Biochem. Biophy. Res. Comm., 330, 1168-1175 (2005). 【IF: 2.281】
Tanaka, N., Nakanishi, M., Kusakabe, Y., Goto, Y., Kitade, Y., and Nakamura, T, K., Crystallization of the N-Ternimal Ankyrin Repeat Domain of the 2-5A-Dependent Endoribonuclease, RNase L, Protein & Peptide Lett., 12, 387-389 (2005). 【IF: 1.735】
Nakanishi, M., Goto, Y. and Kitade, Y., 2-5A Induces a Conformational Change in the Ankyrin-repeat Domain of RNase L, Proteins, 60, 131-138 (2005). 【IF:2.921】
Nakanishi, M., Yabe, S., Tanaka, N., Ito, Y., Nakamura, K, T., and Kitade, Y., Mutational Analyses of Plasmodium falciparum and Human S-adenosylhomocysteine Hydrolases, Mol. Biochem. Parasitol., 143, 146-151 (2005). 【IF: 2.243】
Ohashi, M., Yoshida, K., Kushida, M., Miura, Y., Ohnami, S., Ikarashi, Y., Kitade, Y., Yoshida, T., and Aoki, K., Adenovirus-mediated Interferon alpha Gene Transfer Induces Regional Direct Cytotoxicity and Possible Systemic Immunity Against Pancreatic Cancer, British J. Cancer, 93, 441-449 (2005). 【IF: 4.817】
Ueno, Y., Kato, T., Sato, K., Ito, Y., Inoue, T., Shibata, A., Ebihara, M., and Kitade, Y., Synthesis and Properties of Nucleic Acid Analogs Consisting of a Benzene-phosphate Backbone, J. Org. Chem., 70, 7925-7935 (2005) .【IF: 4.638】
Ito, K., Nakanishi, M., Lee, W.-C., Sasaki, H., Zenno, S., Saigo, K., Kitade, Y., Tanokura, M., Crystal structure of azoreductase AzoR from Escherichia coli, Proc. Japan Acad. Ser. B, 81, 225-228 (2005). 【IF: 2.562】
Nakanishi, M., Tanaka, N., Mizutani, Y., Mochizuki, M., Ueno, M., Nakamura, K. T., and Kitade, Y., Functional characterization of 2 ',5 '-linked oligoadenylate binding determinant of human RNase L. J. Biol. Chem., 280, 41694-41699 (2005). 【IF: 4.600】
Shibata, A., Ueno, Y., Shinbo, K., Nakanishi, M., Matsuda, A., and Kitade, Y., Synthesis of Linked Triple Helical DNAs Possessing High Affinity to Triple Helical DNA Binding Protein, Bioorg. Med. Chem. Lett., 16, 1410-1413 (2006). 【IF: 2.331】
Kitade, Y., Ando, T., Yamaguchi, T., Hori, A., Nakanishi, M., and Ueno, Y., 4-Fluorinated carbocyclic nucleosides: synthesis and inhibitory acticity against S-ademosyl-L-homocysteine hydrolase, Bioorg. Med. Chem., 14, 5578-5583 (2006). 【IF: 2.951】
Ito, K., Nakanishi, M., Lee, W.-C., Sasaki, H., Zenno, S., Saigo, K., Kitade, Y., Tanokura, M., Three-Dimensional Structure of AzoR (azoreductase) from Escherichia coli; AN OXIDEREDUCTASE CONSERVED IN MICROORGANISMS, J. Biol. Chem., 281, 20567-20576 (2006). 【IF: 4.600】
Ueno, Y., Ishihara, S., Ito, Y., and Kitade, Y., Synthesis and hydridization properties of oligonucleotides containing (2S,3R)-9-(2,3,4-trihydroxybutyl)adenine, Nucleosides, Nucleotides, Nucleic Acids, 25, 475-487 (2006). 【IF: 0.894】
Ando, T., Shinohara, H., Luo, X., Kandeel, M., and Kitade, Y., Facile synthesis of 1',2'-cis-β-pyranosyladenine nucleosides, Carbohydr. Res., 342, 2641-2648 (2007).【IF:1.966】
Tsuruta,T., Oh-hashi, K., Ueno, Y., Kitade, Y., Kiuch, K., and Hirata, Y., RNAi knockdown of caspase-activated DNase inhibits rotenone-induced DNA fragmentation in HeLa cells, Neurochem. Int., 50, 601-606 (2007). 【IF: 2.650】
Akao, Y., Nakagawa, Y., Kitade, Y., Kinoshita, T., and Naoe, T., Down-regulation of microRNAs-143 and -145 in B-cell malignancies, Cancer Sci., 98, 1914-1920 (2007).【IF: 3.534】
Morita, K., Kaneko, M., Obika, S., Imanishi, T., Kitade, Y., and Koizumi, M., Biologically stable 2-5A analogs containing 3'-O,4'-C-bridged adenosine as potent RNase L agonists, ChemMedChem., 2, 1703-1707 (2007). 【IF:3.046】
Kumamoto, H., Deguchi, K., Takahashi, N., Tanaka, H, Kitade, Y., Synthesis of novel 4’-modified neplanocin A analogues and their inhibitory activity against S-adenosyl-L-homocysteine hydrolase, Nucleosides Nucleotides & Nucleic Acids, 26, 733-736 (2007). 【IF: 0.894】
Banno, Y., Nemoto, S., Murakami, M., Kimura, M., Ueno, Y., Ohguchi, K., Hara, A., Okano, Y., Kitade, Y., Onozuka, M., Murate, T., Nozawa, Y., Depolarization-Induced Differentiation of PC12 Cells is Mediated by Phospholipase D2 through the Transcription Factor CREB Pathway, J. Neurochem., 104, 1372-1386 (2008). 【IF:4.244】
Ando, T., Iwata, M, Zulfiqar , F, Miyamoto, T, Nakanishi, M, Kitade, Y., Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase, Bioorg. Med. Chem., 16, 3809-3815 (2008).【IF: 2.903】
Kandeel, M., Nakanishi, M., Ando, T., Shazly, K.-E., Yosef, T., Ueno, Y., and Kitade, Y., Molecular cloning, expression, characterization and mutation of Plasmodium falciparum guanylate kinase, Mol.Biochem. Parasitol., 159, 130-133 (2008).【IF: 2.243】
Ando, T., Kojima, K., Chahota, P., Kozaki, A., Milind, N.-D., and Kitade, Y., Synthesis of 4¢-modified noraristeromycins to clarify the effect of the 4¢-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase, Bioorg. Med. Chem. Lett., 18, 2615-2618 (2008). 【IF: 2.331】
Ito, K., Nakanishi, M., Lee, W.-C., Zhi, Y., Sasaki, H., Zenno, S., Saiqo, K., Kitade, Y., and Tanokura, M., Expansion of substrate specificity and catalytic mechanism of azoreductase by X-ray crystallography and site-directed mutagenesis, J. Biol. Chem., 283,13889-13896 (2008).【IF: 4.600】
Kandeel, M. and Kitade, Y., Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase, J. Biochem., 144, 245-250 (2008). 【IF: 3.073】
Kojima, H., Kozaki, A., Iwata, M., Ando, T., and Kitade, Y., Synthesis of 3´,4´-epoxynor- aristeromycin analogs for molecular labeling probe of S-adenosyl-L-homocysteine hydrolase , Bioorg. Med. Chem., 16, 6575-6579 (2008). 【IF: 2.951】
Zulfiqar, F., Kojima, H., Nakanishi, M., Ando, T., and Kitade, Y., Synthesis of carbocyclic 2-subsituted adenine nucleoside and related analogs, Nucleosides Nucleotides & Nucleic Acids, 27, 1153-1157 (2008). 【IF: 0.894】
Ueno, Y., Kawada, K., Naito, Y., Shibata, A., Yoshikawa, K., Kim, H.-S., Wataya, Y., and Kitade, Y., Synthesis and silencing properties of siRNAs possessing lipophilic groups at their 3′-termini, Bioorg. Med. Chem., 16, 7698-7704 (2008). 【IF: 2.951】
Asamitsu, K., Yamaguchi, T., Nakata, K., Hibi, Y., Victoriano, A.-F. B., Imai, K., Onozaki, K., Kitade, Y., and Okamoto, T., Inhibition of human immunodeficiency virus type 1 replication by blocking I kappa B kinase with noraristeromycin, J. Biochem., 144, 581-589 (2008). 【IF: 3.073】
Ueno, Y., Inoue, T., Yoshida, M., Yoshikawa, K., Shibata, A., Kitamura, Y., and Kitade, Y., Synthesis of nuclease-resistant siRNAs possessing benzene-phosphate backbones in their 3′-overhang regions, Bioorg. Med. Chem. Lett., 18, 5194-5196 (2008). 【IF: 2.331】
Ueno, Y., Hirai, M., Yoshikawa, K., Kitamura, Y., Hirata, Y., Kiuchi, K., and Kitade, Y., Synthesis and properties of siRNAs 5′-amino-2′,5′-dideoxy-2′α-fluororibonucleosides, Tetrahedron, 64, 11328-11334 (2008). 【IF: 2.803】
Endo, S., Matsunaga, Y., Kitade,Y., Ohno, S., Tajima, K., El-Kabbani, O., Hara, A.,
Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase, Biochem. Biophys. Res. Commun., 377, 1326-1330 (2008).【IF: 2.281】
Endo, S., Matsunaga, T., Mamiya, H., Hara, A., Kitade, Y., Tajima, K., and El-Kabbani, O., Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress, Chem. Biol. Interact.,178, 151-157 (2009). 【IF: 2.982】
Kandeel, M., Ando, T., Kitamura, Y., Abdel-Aziz, M., and Kitade, Y., Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for development of a new drug target, Parasitology, 136, 11-25 (2009). 【IF: 2.350】
Kitamura, Y., Taniguchi, K., Maegawa, T., Monguchi, Y., Kitade, Y., and Sajiki, H., Copper/HP20: novel and polymer-supported copper catalyst for Huisgen cycloaddition, Heterocycles, 77, 521-532 (2009). 【IF:0.908】
Ueno, Y., Yoshikawa, K., Kitamura, Y., Kitade, Y., Effect of incorporation of alkyl linkers into siRNAs on RNA interference, Bioorg. Med. Chem. Lett., 19, 875-877 (2009). 【IF: 2.331】
Ueno, Y., Watanabe, Y., Shibata, A., Yoshikawa, K., Takano, T., Kohara, M.., Kitade, Y., Synthesis of nuclease-resistant siRNAs possessing universal overhangs, Bioorg. Med. Chem., 17, 1974-1981 (2009). 【IF: 2.951】
Naito, T., Yokogawa, T., Takatori, S., Goda, K., Hiramoto, A., Sato, A., Kitade, Y., Sasaki, T., Matsuda, A., Fukushima, M., Wataya, Y., and Kim, H.-S., Role of RNase L in apoptosis induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine, Cancer Chemother. Pharmacol., 63, 837-850 (2009). 【IF: 2.571】
Kandeel, M., Miyamoto, T. and Kitade, Y., Bioinformatics, enzymologic properties and comprehensive tracking of Plasmodium falciparum nucleoside diphosphate kinase, Biol. Pharm. Bull., 32, 1321-1327 (2009). 【IF:1.778】
Endo, S., Matsunaga, T., Mamiya, H., Ohta, C., Soda, M., Kitade, Y., Tajima, K., Zhao, HT., El-Kabbani, O., Hara, A., Kinetic studies of AKR1B10, human aldose reductase-like protein: Endogenous substrates and inhibition by steroids, Arch. Biochem. Biophys., 487, 1-9 (2009).【IF: 3.043】
Ueno, Y., Kawamura, A., Takasu, K., Komatsuzaki, S., Kato, T., Kuboe, S., Kitamura, Y., Kitade, Y., Synthesis and properties of a novel molecular beacon containing a benzene-phosphate backbone at its stem moiety, Org. Biomol.Chem., 7, 2761-2769 (2009).【IF: 3.487】
Kumamoto, H., Deguchi, K., Wagata, T., Furuya, Yuu., Odanaka, Y., Kitade, Y., Tanaka, H., Radical-mediated stannylation of vinyl sulfones: access to novel 4 '-modified neplanocin A analogues, Tetrahedron., 65, 8007-8013 (2009). 【IF: 2.803】
Ueno, Y., Komatsuzaki, S., Takasu, K., Kawai, S., Kitamura, Y., and Kitade, Y., Synthesis and Properties of Oligonucleotides Containing Novel Fluorescent Biaryl Units, Eur. J. Org. Chem., 28, 4763-4769 (2009). 【IF: 3.154】
Akao, Y., Nakagawa, Y., Hirata, I., Iio, A., Itoh, T., Kojima, K., Nakashima, R., Kitade, Y., and Naoe, T., Role of anti-oncomirs miR-143 and -145 in human colorectal Tumors, Cancer Gene Therapy, 17, 398-408 (2010). 【IF: 2.553】
Nagaoka, K.., Kitamura, Y., Ueno, Y., Kitade, Y., 5’-O-Dephosphorylated 2’,5’-oligoadenylate (2-5A) with 8-methyladenosine at the 20-terminus activates human RNase L, Bioorg. Med. Chem. Lett., 20, 1186-1188 (2010). 【IF: 2.331】
Aoki, K., Tanaka, N., Kusakabe, Y., Fukumi, C., Haga, A., Nakanishi, M., Kitade, Y., Nakamura, KT., Crystallization and preliminary X-ray crystallographic study of phosphoglucose isomerase from Plasmodium falciparum, Acta Crystallogr. F., 66, 333-336 (2010). 【IF: 0.568】
Umeda, T., Tanaka, N., Kusakabe, Y., Nakanishi, M., Kitade, Y., Nakamura, KT., Crystallization and preliminary X-ray crystallographic study of 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Plasmodium falciparum, Acta Crystallogr. F., 66, 330-332 (2010). 【IF: 0.568】
Ishihara, M., Kusakabe, Y., Ohsumichi, T., Tanaka, N., Nakanishi, M., Kitade, Y., Nakamura, KT., Crystallization of mouse S-adenosyl-L-homocysteine hydlase, Acta Crystallogr. F., 66, 313-315 (2010). 【IF: 0.568】
Endo, S., Matsunaga, T., Kuwata, K., Zhao, HT., El-Kabbani, O., Kitade, Y., Hara, A., Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10, Bioorg. Med. Chem., 18, 2485-2490 (2010). 【IF: 2.951】
Kitamura, Y., Sako, S., Tsutsui, A., Monguchi, Y., Maegawa, T., Kitade, Y., Sajiki, H., Ligand-Free and Heterogeneous Palladium on Carbon-Catalyzed Hetero-Suzuki-Miyaura Cross-Coupling, Advanced Synthesis & Catalysis, 352, 718-730 (2010). 【IF: 5.542】
Kuboe, S., Yoda, M., Ogata, A., Kitade, Y., Tomari, Y., Ueno, Y., Diazirine-containing RNA photocrosslinking probes for the study of siRNA-protein interactions, Chem. Commun., 46, 7367-7369 (2010). 【IF: 6.718】
Endo, S., Matsunaga, T., Kuragano, T., Ohno, S., Kitade, Y., Tajima, K., El-Kabbani, O., Hara, A., Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10), Arch. Biochem. Biophys., 503, 230-237 (2010). 【IF: 3.043】
Sato, A., Naito, T., Hiramoto, A., Goda, K., Omi, T., Kitade, Y., Sasaki, T., Matsuda, A., Fukushima, M., Wataya, Y., Kim, H.-S., Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line, Febsj., 27, 4464-4473 (2010).【IF: 3.986】
Ogata, A., Furukawa, C., Sakurai, K., Iba, H., Kitade, Y., Ueno, Y., Biaryl modification of the 5 '-terminus of one strand of a microRNA duplex induces strand specificity, Bioorg. Med. Chem. Lett., 20, 7299-7302 (2010). 【IF: 2.331】
Kandeel, M., and Kitade, Y., Substrate specificity and nucleotides binding properties of NM23H2/nucleoside diphosphate kinase homolog from Plasmodium falciparum, J. Bioenerg. Biomembr., 42, 361-369 (2010). 【IF:2.708】